In a large nonstick skillet, heat oil over medium heat. Add onion and garlic; cook 3 minutes. Stir in cream cheese and Boursin until melted. Add milk, cream and wine, stirring constantly.
Add seafood seasoning, Worcestershire, hot sauce and, if desired, red pepper flakes. Stir in crab, spinach and cheddar cheese until cheese melts and mixture is bubbly. Serve warm with blue tortilla chips.
Editor’s Note: Boursin garlic and fine herbs cheese, sold in a 5.2-ounce package, has a firmer texture than the spreadable cheese product.