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45 Southwest Casseroles to Kick Mealtime Up a Notch

These southwest casseroles will be a hot commodity (literally!) around your kitchen table.

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Southwestern Turkey Bake Exps Chmz19 49870 B10 30 6b 3

Southwestern Turkey Bake

I make this turkey bake as a way to get my husband and nieces to eat their vegetables. It's also perfect if you're wondering what to do with leftover turkey. This creamy entree will fill you up fast. —Crystal Kolady, Henrietta, New York
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Easy Chiles Rellenos Casserole Exps Gbbz19 4592 C11 08 4b 9

Easy Chiles Rellenos Casserole

I love green chiles and cook with them often when I entertain. This easy version of the classic Mexican dish gives you big pepper taste in every meaty bite. —Nadine Estes, Alto, New Mexico
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Taco Cornbread Casserole Exps 13x9bz19 165634 E10 10 3b 18

Taco Cornbread Casserole

A whole can of chiles adds fire to this cornbread casserole. For less heat, you can use just enough of the can for your taste. —Lisa Paul, Terre Haute, Indiana
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Pork And Green Chili Casserole Exps Opbz18 1218 E06 05 5b 11

Pork and Green Chile Casserole

I work at a local hospital and another job part time, so I'm always on the lookout for good, quick recipes to fix for my family. Some of my co-workers and I exchange recipes. This zippy casserole is one that was brought to a picnic at my house. People raved over it. —Dianne Esposite, New Middletown, Ohio
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Mexican Egg Casserole

Tomatoes and green chiles give color and zip to this extra cheesy egg bake. It’s a favorite for breakfast or brunch, but it can be enjoyed for lunch or supper, too. —Mary Steiner, West Bend, Wisconsin
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Cheesy Chili Casserole Exps Opbz18 4281 E06 05 3b 12

Cheesy Chile Casserole

A short list of ingredients packs full flavor in this easy-to-assemble casserole. Serve it as the star of your next southwestern meal. —Phyllis Bidwell, Las Vegas, Nevada
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Baked Beef Tacos

This taco recipe takes classic taco ingredients and gives them a fresh approach by baking the shells upright in refried beans and tomatoes. The bottom gets soft, and the top stays crisp and crunchy. —Patricia Stagich, Elizabeth, New Jersey
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Southwestern Casserole Exps Thn16 15969 D06 22 2b 3

Southwestern Casserole

I've been making this mild family-pleasing southwest casserole recipe for years. It tastes wonderful, fits nicely into our budget and, best of all, makes a second one to freeze and enjoy later. —Joan Hallford, North Richland Hills, Texas
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Exps188704 Sd153323a06 04 1b 7

Chicken Chiles Rellenos Casserole

My husband likes Mexican food and casseroles, so I combined the two. This chicken with poblanos and chiles satisfies our craving for dinner at a Mexican restaurant. —Erica Ingram, Lakewood, Ohio
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Chili Beef Cornbread Casserole

This recipe is my potluck standby. And when I hear that someone may need a comforting home-cooked meal, I bring them this casserole. —Lorraine Espenhain, Corpus Christi, Texas
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Cheesy Fiesta Beef Casserole Exps Sdas18 218105 D03 28  2b 6

Cheesy Fiesta Beef Casserole

Over the years I’ve tweaked this recipe to end up with a wonderful, quick weeknight meal. Feel free to spice it up with jalapenos, if you prefer a little more heat. —Joan Hallford, North Richland Hills, Texas
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Southwestern Breakfast Slow-Cooker Casserole

I created this recipe for a breakfast-for-dinner meal one day, and now it’s become a favorite on chilly mornings. Such a wonderful aroma! Using extra-sharp cheddar cheese instead of the milder types allows you to use less, while giving you an extra boost of flavor. —Lisa Renshaw, Kansas City, Missouri
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Salsa Verde Chicken Casserole Exps Opbz18 164054 B06 07 3b 5

Salsa Verde Chicken Casserole

This is a rich and tasty combination of all the Tex-Mex dishes blended into one packed, beautiful casserole. Best of all, it’s ready in only half an hour! —Janet McCormick, Proctorville, Ohio
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Southwest Vegetarian Bake Exps Ghbz18 26649 B08 08 3b 3

Southwest Vegetarian Bake

This veggie-packed casserole hits the spot on chilly nights. It's a healthy canned vegetable recipe that's perfect anytime I have a taste for Mexican food with all the fixings. —Patricia Gale, Monticello, Illinois
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Tex-Mex Cheese Strata

Tortilla chips add a little fun to this south-of-the-border brunch. For a spicier taste, substitute pepper Jack for the Monterey Jack cheese. —Vickie Lowrey, Fallon, Nevada
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Creamy Green Chile Chicken Cobbler

Biscuity crumbs take this family-friendly combo of rotisserie chicken and cheesy, creamy green enchilada sauce over the top. —Johnna Johnson, Scottsdale, Arizona
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Sweet Potato Enchilada Stack Exps Chmz19 49726 E10 30 9b 3

Sweet Potato Enchilada Stack

These sweet potato stacks have a spicy kick the whole family will love. Mexican flavors abound in this awesome enchilada stack jam-packed with black beans and sweet potato. —Taste of Home Test Kitchen
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Cobre Valley Casserole

We live in southeastern Arizona, in a part of the state known as Cobre Valley. Cobre is Spanish for copper, which is mined here. People in this area have enjoyed variations of this recipe for many years. —Carolyn Deming, Miami, Arizona
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Chiles Rellenos Quiche Exps Hscbz17 29023 B07 21 6b 5

Chiles Rellenos Quiche

To me, nothing sparks up a meal more than the smoky flavor of roasted green chiles. This is a quick and easy recipe, and I usually have the ingredients on hand, so when I don’t know what to fix for dinner, I make this quiche. —Linda Miritello, Mesa, Arizona
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Taco Noodle Dish

I got creative while we were housebound during a snowstorm one winter...and used ingredients I had on hand to come up with this hearty casserole. Later, I modified it so it has less fat and fewer calories. —Judy Munger, Warren, Minnesota
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Beef N Biscuit Bake Exps Gbbz19 3959 E11 07 6b 2

Beef 'n' Biscuit Bake

This recipe is quick, easy and satisfying. With its beef and corn combo, it's cozy cuisine at its best! —Erin Schneider, St. Peters, Missouri
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Exps4993 Fm153592c03 18 3b 26

Chicken Tortilla Bake

Mother frequently made this comforting chicken tortilla casserole when I was growing up. Our family would scrape the pan clean. Chicken, cheese and zippy green chiles are a mouthwatering mix. —Jerri Moror, Rio Rancho, New Mexico
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Exps38746 B163857d11 03 1b 7

Chicken Taco Quiche

I wanted to make a quiche but didn't want the usual flavors, so I used ingredients I had in my pantry and refrigerator to come up with this recipe. I was surprised at the great taste and how well the flavors came together. My neighbor asked for the recipe and had the same success! —Tamie Bradford, Grand Forks AFB, North Dakota
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Spicy Nacho Bake Exps Gbbz19 37971 E11 13 13b 9

Spicy Nacho Bake

I made this hearty, layered southwestern casserole for a dinner meeting once, and now I'm asked to bring it every time we have a potluck. Everybody loves the beefy bean filling and crunchy, cheesy topping. —Anita Wilson, Mansfield, Ohio
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Chicken and Chiles Casserole

This casserole makes good use of leftover meat and is very filling. —Lois Keel, Alburquerque, New Mexico
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Breakfast Burrito Casserole Exps Bbbz16 77315 05b 26 1b 6

Breakfast Burrito Casserole

A friend gave me this burrito casserole recipe and I modified it to fit our family. It's perfect for a brunch, because you can prep it the night before and bake it the next morning. —Krista Yoder, Due West, South Carolina
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Green Chile Quiche Squares

Chilies add spark to this cheesy quiche. You can vary the flavor based on the kind of croutons you buy. I like to serve fresh fruit on the side. —Connie Willson, Huntington Beach, California
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Chile Tamale Pie

Chile Tamale Pie

This is a crowd-pleasing potluck dish that’s easy to prepare. A little heat, a little sweet, and big time authentic southwestern flavor. There is no substitute for fresh ground chili. A small food processor on high speed may be used to grind chilies and cumin, or use a dedicated coffee grinder for fresh spices (a great $15 investment for fresh spices anytime—your palate will thank you)! —Ralph Stamm, Dayton, Ohio
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Sausage Tortilla Breakfast Bake Exps Lsbz18 77381 C01 18  1b 105

Sausage Tortilla Breakfast Bake

This casserole is perfect for a special brunch. It combines the spices of the Southwest with the comfort of a hearty breakfast. You can spice it up by adding cayenne and hot peppers, or mellow it by replacing the tomatoes and green chiles with mild salsa. It’s versatile and easy—no wonder it’s a longtime family favorite. —Darlene Buerger, Peoria, Arizona
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Exps149267 Thca2916394b02 01 15b Web 6

Chicken and Olive Mole Casserole

My southwestern chicken casserole makes the perfect party dish when you're looking for something a little out of the ordinary. The mole sauce lends an authentic flavor, and folks are always pleasantly surprised to taste a little sweetness from the chocolate. —Barbara White, Livingston, Texas
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Fiesta Breakfast Bake

I get a kick out of making breakfast for a crowd when I have weekend guests, and my family also loves breakfast for dinner. I created this dish by combining my family’s favorite southwest flavors in an all-in-one-pan recipe. —Whitney Gilbert, Smithville, Missouri
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Spicy Enchilada Casserole

This zippy Mexican casserole is a real winner at our house. It’s so flavorful and filling, we usually just accompany it with rice and black beans. If your family has spicier tastes, increase the chili powder and use a medium or hot salsa. —Julie Huffman, New Lebanon, Ohio
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Exps34789 Bhr143425c05 15 4b 2

Green Chili Egg Puff

Green chilies add a touch of Southwest flavor to this fluffy egg dish. The cottage cheese offers nice texture, and people always love the gooey Montery Jack cheese melted throughout. —Laurel Leslie, Sonora, California
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Exps17460 B163857c10 23 3b 2

Southwest Sausage Bake

This layered tortilla dish is not only delicious, but it’s a real time-saver because it’s put together the night before. The tomato slices provide a nice touch of color. I like to serve this crowd-pleasing casserole with muffins and fresh fruit. —Barbara Waddel, Lincoln, Nebraska
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Fiesta Cornbread & Sausage Strata

I like to break away from traditional breakfast bakes, so I experimented and came up with this sweet-savory cornbread and sausage egg bake. It’s easy to prepare and a wonderful make-ahead morning meal. —Ellen Woodham-Johnson, Matteson, Illinois
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Chiles Rellenos Breakfast Bake

My family loves anything with a Southwestern flavor, so I turned classic chiles rellenos into a breakfast casserole. They became fans in an instant. —Joan Hallford, North Richland Hills, Texas
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Exps193064 Sd163614b12 03 10b 7

Chicken Tamale Bake

When I serve this Mexican-style casserole, everyone scrapes the plate clean. Offer fresh toppings like green onions, tomatoes and avocado. —Jennifer Stowell, Smithville, Missouri
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Fold Over Tortilla Bake Exps Mtbz18 5912 B03 13 10b 3

Fold-Over Tortilla Bake

Here’s something a little different to shake up taco night. But don’t reserve this zippy dish for a weeknight—it’s perfect for potlucks and serving company, too. something a little different from the usual tacos. It's special enough for potlucks or dinner guests. —Deborah Smith, DeWitt, Nebraska
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Tex-Mex Summer Squash Casserole

Mild-flavored yellow squash gets a big boost from flavor-packed chiles, jalapenos and red onion. This side dish also works with zucchini. —Tommy Lombardo, Euclid, Ohio
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Chili Mac Casserole Exps Dsbz17 15634 C01 13 1b 19

Chili Mac Casserole

This cheesy casserole uses several of my family's favorite ingredients, including macaroni, kidney beans, tomatoes and cheese. Just add a leafy salad for a complete meal. —Marlene Wilson, Rolla, North Dakota
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Grandma S Rice Dish Exps Gbbz19 16478 C11 27 10b 2

Grandma's Rice Dish

My grandmother often made this casserole when I was young. I forgot about it until one day I found myself adding the same ingredients to leftover rice. The memories came flooding back. —Lorna Moore, Glendora, California
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Spicy Egg Bake Exps Bfbz19 31427 E01 18 1b 4

Spicy Egg Bake

This family favorite makes a wonderful brunch dish served with muffins and fresh fruit. It's also a terrific way to use up extra taco meat. Adjust the heat by choosing a hotter or milder salsa. —Michelle Jibben, Gilbert, Arizona
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Chicken Enchilada Bake Exps Sdon16 44348 B06 07 7b 6

Chicken Enchilada Bake

Your family is going to gobble up this cheesy, southwestern and easy chicken enchilada casserole…and will ask for it again and again. It’s real comfort food! —Melanie Burns, Pueblo West, Colorado
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Sassy Southwest Stuffed Shells

When I was a child, my mom made this dish quite often. When I came across her recipe on an index card, I quickly copied it. Over the years, I have made very few changes to retain that taste-of-home memory. —Kellie Braddell, West Point, California
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Burrito Bake Exps Thn16 13710 D06 21 1b 31

Burrito Bake

Back when I was in college, my roommate would frequently make this economical baked burrito casserole. It's so easy to put together, and one serving goes a long way. —Cindee Ness, Horace, North Dakota

Annamarie Higley
Annamarie Higley is an Associate Print Editor for Taste of Home magazine, as well as the brand's special issue publications. A midwestern transplant originally from the San Francisco Bay Area, she enjoys hiking, trivia-ing, and—you guessed it!—all things cooking and baking.